glucocorticoids


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[See also Corticosteroid Receptors and Unipolar Depression.]

Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, Hochberg RB, McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA
International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors.
Pharmacol Rev. 2006 Dec;58(4):782-97. [Full Text]

Korte SM.
Corticosteroids in relation to fear, anxiety and psychopathology.
Neurosci Biobehav Rev 2001 Mar;25(2):117-42
[Abstract]

McEwen, Bruce S.
Protective and Damaging Effects of Stress Mediators
N Engl J Med 1998 338: 171-179 [Full Text]

Wolkowitz, Owen M., Reus, Victor I.
Treatment of Depression With Antiglucocorticoid Drugs
Psychosom Med 1999 61: 698-711 [Full Text]

Muller M, Holsboer F, Keck ME.
Genetic modification of corticosteroid receptor signalling: novel insights into pathophysiology and treatment strategies of human affective disorders.
Neuropeptides 2002 Apr-Jun;36(2-3):117-31 [Abstract]

Lupien, SJ;de Leon, M;de Santi, S;Convit, A;Tarshish, C;Thakur, M;McEwen, BS;Hauger, RL;Meaney, MJ
Cortisol levels during human aging predict hippocampal atrophy and memory deficits
NATURE NEUROSCIENCE 1: (1) 69-73 MAY 1998 [Abstract]

Plevy SE.
Corticosteroid-sparing treatments in patients with Crohn's disease.
Am J Gastroenterol 2002 Jul;97(7):1607-17 [Abstract]

Dwivedi, Yogesh, Pandey, Ghanshyam N.
Adrenal Glucocorticoids Modulate [3H]Cyclic AMP Binding to Protein Kinase A (PKA), Cyclic AMP-Dependent PKA Activity, and Protein Levels of Selective Regulatory and Catalytic Subunit Isoforms of PKA in Rat Brain
J Pharmacol Exp Ther 2000 294: 103-116 [Full Text]

Dwivedi, Yogesh, Rizavi, Hooriyah S., Rao, Jagadeesh S., Pandey, Ghanshyam N.
Modifications in the Phosphoinositide Signaling Pathway by Adrenal Glucocorticoids in Rat Brain: Focus on Phosphoinositide-Specific Phospholipase C and Inositol 1,4,5-Trisphosphate
J Pharmacol Exp Ther 2000 295: 244-254 [Full Text]

Lyons, David M., Lopez, Jacqueline M., Yang, Chou, Schatzberg, Alan F.
Stress-Level Cortisol Treatment Impairs Inhibitory Control of Behavior in Monkeys
J. Neurosci. 2000 20: 7816-7821 [Full Text]

Starkman, Monica N., Giordani, Bruno, Berent, Stanley, Schork, M. Anthony, Schteingart, David E.
Elevated Cortisol Levels in Cushing's Disease Are Associated With Cognitive Decrements
Psychosom Med 2001 63: 985-993 [Full Text]

Lupien, SJ;Gillin, CJ;Hauger, RL
Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: A dose-response study in humans
BEHAVIORAL NEUROSCIENCE 113: (3) 420-430 JUN 1999 [Abstract]

de Kloet, E. Ronald, Vreugdenhil, Erno, Oitzl, Melly S., Joels, Marian
Brain Corticosteroid Receptor Balance in Health and Disease
Endocr Rev 1998 19: 269-301 [Full Text]

Mizuno, Makoto, Yamada, Kiyofumi, Olariu, Ana, Nawa, Hiroyuki, Nabeshima, Toshitaka
Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats
J. Neurosci. 2000 20: 7116-7121 [Full Text]

Bergh, Florian Then, Kumpfel, Tania, Grasser, Annette, Rupprecht, Rainer, Holsboer, Florian, Trenkwalder, Claudia
Combined Treatment with Corticosteroids and Moclobemide Favors Normalization of Hypothalamo-Pituitary-Adrenal Axis Dysregulation in Relapsing-Remitting Multiple Sclerosis: A Randomized, Double Blind Trial
J Clin Endocrinol Metab 2001 86: 1610-1615 [Full Text]

Raber, Jacob, O'Shea, Ross D., Bloom, Floyd E., Campbell, Iain L.
Modulation of Hypothalamic-Pituitary-Adrenal Function by Transgenic Expression of Interleukin-6 in the CNS of Mice
J. Neurosci. 1997 17: 9473-9480 [Full Text]

Sapolsky, Robert M., Romero, L. Michael, Munck, Allan U.
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions
Endocr Rev 2000 21: 55-89 [Full Text]

Robert Fraser, Mary C. Ingram, Niall H. Anderson, Caroline Morrison, Eleanor Davies, and John M. C. Connell
Cortisol Effects on Body Mass, Blood Pressure, and Cholesterol in the General Population
Hypertension 33: 1364-1368, 1999. [Full Text]

Watts, Alan G., Sanchez-Watts, Graciela
Interactions between Heterotypic Stressors and Corticosterone Reveal Integrative Mechanisms for Controlling Corticotropin-Releasing Hormone Gene Expression in the Rat Paraventricular Nucleus
J. Neurosci. 2002 22: 6282-6289 [Abstract]

Almawi, Wassim Y., Melemedjian, Ohannes K.
Molecular mechanisms of glucocorticoid antiproliferative effects: antagonism of transcription factor activity by glucocorticoid receptor
J Leukoc Biol 2002 71: 9-15 [Abstract]

Sarnyai, Zoltan, Shaham, Yavin, Heinrichs, Stephen C.
The Role of Corticotropin-Releasing Factor in Drug Addiction
Pharmacol Rev 2001 53: 209-244 [Full Text]

J Herbert
Fortnightly review: Stress, the brain, and mental illness
BMJ 1997; 315: 530-535. [Full Text]

George P. Chrousos, and Philip W. Gold
A Healthy Body in a Healthy Mind—and Vice Versa—The Damaging Power of "Uncontrollable" Stress
J. Clin. Endocrinol. Metab. 83: 1842-1842, 1998. [Full Text]

Lorraine I. McKay, and John A. Cidlowski
Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-B and Steroid Receptor-Signaling Pathways
Endocr. Rev. 20: 435-459, 1999. [Full Text]

Steinberg, Regis, Alonso, Richard, Griebel, Guy, Bert, Lionel, Jung, Mireille, Oury-Donat, Florence, Poncelet, Martine, Gueudet, Christiane, Desvignes, Christophe, Le Fur, Gerard, Soubrie, Philippe
Selective Blockade of Neurokinin-2 Receptors Produces Antidepressant-Like Effects Associated with Reduced Corticotropin-Releasing Factor Function
J Pharmacol Exp Ther 2001 299: 449-458 [Abstract]

Dwivedi, Yogesh, Pandey, Ghanshyam N.
Repeated Administration of Dexamethasone Increases Phosphoinositide-Specific Phospholipase C Activity and mRNA and Protein Expression of the Phospholipase C {beta}1 Isozyme in Rat Brain
J Neurochem 1999 73: 780-790 [Abstract]

Dwivedi, Yogesh, Pandey, Ghanshyam N.
Administration of Dexamethasone Up-Regulates Protein Kinase C Activity and the Expression of {gamma} and {epsilon} Protein Kinase C Isozymes in the Rat Brain
J Neurochem 1999 72: 380-387 [Abstract]

Belanoff, Joseph K., Kalehzan, Michelle, Sund, Brenda, Fleming Ficek, Shelley K., Schatzberg, Alan F.
Cortisol Activity and Cognitive Changes in Psychotic Major Depression
Am J Psychiatry 2001 158: 1612-1616
"CONCLUSIONS: Psychotic major depression is endocrinologically different from nonpsychotic major depression and produces cognitive changes distinct from those seen in nonpsychotic major depression." [Abstract]

Nelson, J. Craig, Davis, John M.
DST Studies in Psychotic Depression: A Meta-Analysis
Am J Psychiatry 1997 154: 1497-1503 [Full Text]

Lindley, SE;Bengoechea, TG;Schatzberg, AF;Wong, DL
Glucocorticoid effects on mesotelencephalic dopamine neurotransmission
NEUROPSYCHOPHARMACOLOGY 21: (3) 399-407 SEP 1999 [Abstract]

Roy, Adip, Mittal, Navdha, Zhang, Huaibo, Pandey, Subhash C.
Modulation of Cellular Expression of Glucocorticoid Receptor and Glucocorticoid Response Element-DNA Binding in Rat Brain during Alcohol Drinking and Withdrawal
J Pharmacol Exp Ther 2002 301: 774-784 [Abstract]

Van de Kar, LD;Blair, ML
Forebrain pathways mediating stress-induced hormone secretion
FRONTIERS IN NEUROENDOCRINOLOGY 20: (1) 1-48 JAN 1999 [Abstract]

Ni, Yan G., Gold, Stephen J., Iredale, Philip A., Terwilliger, Rose Z., Duman, Ronald S., Nestler, Eric J.
Region-Specific Regulation of RGS4 (Regulator of G-Protein-Signaling Protein Type 4) in Brain by Stress and Glucocorticoids: In Vivo and In Vitro Studies
J. Neurosci. 1999 19: 3674-3680 [Full Text]

TURNBULL, ANDREW V., RIVIER, CATHERINE L.
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
Physiol. Rev. 1999 79: 1-71 [Full Text]

McEwen, Bruce S.
STRESS AND HIPPOCAMPAL PLASTICITY
Annu. Rev. Neurosci. 1999 22: 105-122 [Abstract]

HEATHER E. EDWARDS, and W. MCINTYRE BURNHAM
The Impact of Corticosteroids on the Developing Animal
Pediatr Res 50: 433-440, 2001. [Abstract]

O'CONNOR, T.M., O'HALLORAN, D.J., SHANAHAN, F.
The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia
QJM 2000 93: 323-333 [Full Text]

Raber, Jacob, Akana, Susan F., Bhatnagar, Seema, Dallman, Mary F., Wong, Derek, Mucke, Lennart
Hypothalamic-Pituitary-Adrenal Dysfunction in Apoe-/- Mice: Possible Role in Behavioral and Metabolic Alterations
J. Neurosci. 2000 20: 2064-2071 [Full Text]

Quan, Ning, He, Lingli, Lai, Wenmin, Shen, Tiansheng, Herkenham, Miles
Induction of Ikappa Balpha mRNA Expression in the Brain by Glucocorticoids: A Negative Feedback Mechanism for Immune-to-Brain Signaling
J. Neurosci. 2000 20: 6473-6477 [Full Text]

Sargent PA , Williamson DJ , Cowen PJ
Brain 5-HT neurotransmission during paroxetine treatment.
Br J Psychiatry, 172(): 49-52 1998 [Abstract]


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